This 2021 Observatory Report is an observational study on the people excluded from mainstream healthcare services in Europe and provides a snapshot of the state of Universal Healthcare Coverage (UHC). The report contains data and testimonies collected at Médecins du Monde/Doctors of the World (MdM) programmes in seven European countries (Belgium, France, Germany, Greece, Luxembourg, Sweden, and the United Kingdom) between January 2019 and December 2020.